CellColt
Selective multiradial,
micro-aspiration system of autologous bone marrow tissue for stem cell therapy
The most studied source of mesenchymal stem cells (MSCs) is bone marrow. They are particularly abundant in the fraction of mononucleated cells.
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MSCs are conductors of tissue reparation and regeneration, functions that are expleted through the secretion of trofic mediators. Therefore, MSCs are likely the most interesting cells when it comes to orthopedic applications given their potential to differentiate both in bone and cartilage.
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A comparative study on the quantity of nucleous cells generated from different bone sources highlighted how bone marrow aspirate from the posterior iliac crest provides the highest concentration of nucleous cells, (25.1-54.7)x10 cells/ml. The best autologous sources of MSCs in decreasing order of cell abundance have been ranked as: inferior iliac crest, proximal humerus, distal femur, vertebral bodies, humerus head, proximal tibia, heel bone, and distal tibia.
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The quantity of MSCs in the bone marrow aspiration also depends on factors like the age of the patient, the technique of aspiration employed, and the risk of diluition of peripheral blood.
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IT HAS BEEN PROVEN THAT BY PERFORMING MICRO ASPIRATIONS WITH SMALL VOLUME SYRINGES, HIGHER CONCENTRATIONS OF MONONUCLEAR CELLS BM-MNCS CAN BE OBTAINED
CellColt creates an exclusively later and radial aspiration flow, thanks to the presence of an internal aspiration closed-end cannula. This characteristic minimizes the dilution of the marrow aspirate with peripheral blood, an improvement compared to the traditional open-end cannulas which collect an aspirate with a high presence of peripheral blood.
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LATERAL MULTI RADIAL ASPIRATION FLOW ON 4 LEVELS
MAXIMIZES RETRIEVAL OF PROGENITOR AND MESENCHIMAL CELLS
MINIMIZES DILUITION WITH PERIPHERAL BLOOD
MICRO ASPIRATION OF 2ML
SLIDING BLOCK
The patented "Sliding Block" located on the handle allows the internal aspiration cannula to retreat, aligning and opening new side holes on four different levels.
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The alternated opening of 6 out of 12 of holes located along the cannula allows the aspiration of the marrow on different depths. The cannula exploits a larger area of aspiration inside the marrow, using only one site of entry.
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The execution of the micro aspirations of 2ml on multiple levels maximizes the capacity of cell retrieval.
Product reference: PSH1D2XXYY
XX = Gauge
YY = Minimum Length
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